Trometamol hydrochloride (Tris-HCl) is used in many applications within molecular biology laboratories as a buffering agent. It is also extensively employed in the preparation of antibody drugs, nucleic acid drugs, and vaccines.
NMPA CDE registration no.: F20220000346
USFDA DMF no.: 038022
| Product Name | Trometamol hydrochloride；TRIS-HCL |
| Chemical Name | Tris(hydroxymethyl)aminomethane hydrochloride |
| CAS No. | 1185-53-1 |
| NMPA CDE registration no. | F20220000346 |
| USFDA DMF No. | 038022 |
| Quality grade | Injection |
| Quality standards | Comply with ChP, USP, EP or other pharmacopoeia standards |
| Molecular Formula | C4H12CINO3 |
| Applications and examples | Monoclonal and bispecific antibodies, Antibody-drug conjugates (ADC), liposomes, nucleic acid drugs, vaccines and other premium preparation |
| Product code | A03002 |
| Package sizes | 1kg |
| Storage condition | It should be stored in well-closed containers, protected from light. It should be retested every 2 years when used and stored properly. |
Tris-HCl offers the following advantages: high solubility in water resulting in clear solutions; high purity up to 99.6%, with stable performance; no precipitation with certain metal ions (such as calcium and magnesium); low ionic strength; superior performance over traditional phosphate buffer systems in enzyme assays.
Tris-HCl effectively stabilizes the pH of a solution and maintains the physical stability of macromolecular drugs to prevent their degradation or aggregation during the experiment.
Excellent pH stability (7.0-9.0) and buffering capacity in biochemical assays and cell culture systems.
Available in multiple formulations (powder, solution) and packaging options with strict QC certifications.
If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.
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