HSPC stands for Hydrogenated soy phosphatidylcholine.HSPC (main component DSPC) is obtained by reducing the fatty acid type through semi-synthetic method of hydrogenation and hydrogenation,The physicochemical properties are more stable and can meet the requirements of the pharmaceutical industry. It is a common phospholipid for developing liposomes.
| Product Name | Hydrogenated soy phosphatidylcholine |
| Chemical Name | 1-palmitoyl-2-stearoyl-sn-glycero-3- phosphatidylcholine |
| CAS No. | 92128-87-5 |
| NMPA CDE registration no. | F20170000148 |
| USFDA DMF No. | 027072 |
| Quality grade | Injectable pharmaceutical grade |
| Quality standards | Conforms with USP, EP, JP, ChP standards |
| Molecular Formula | C42H84NO8P |
| Applications and examples | HSPC is hydrogenated soybean lecithin (pharmaceutical injection grade), a semi-synthetic phospholipid. Its content of 1,2-distearoyl lecithin is not less than 98%, suitable for the preparation of liposomes. As a membrane material, it has been widely used in the R&D of liposome drugs and the formulations of marketed products, and has also been used in multiple liposome products in clinical stage, such as liposomal lurtotecan. |
| Product code | N01003 |
| Package sizes | 1kg |
| Storage condition | It should be stored at -20℃ in well-closed containers, protected from light. Avoid exposure to strongly oxidizing media. It is valid for 60 months when used and stored properly, and it should be retested every year thereafter. |
HSPC hydrogenated soy phosphatidylcholine, also known as CAS 92128 87 5, is a commonly used semi-synthetic phospholipid. HSPC hydrogenated soy phosphatidylcholine (92128 87 5) can be dissolved in appropriate organic solvent together with phospholipids and drugs, rotary-evaporated in a 55-degree water bath, and vacuumized to form a thin film. HSPC hydrogenated soy phosphatidylcholine can also be dissolved in an appropriate organic solvent together with phospholipids, and slowly and uniformly injected into an aqueous solution containing Doxil in a 55-degree water bath with rapid stirring to form a uniform colostrum. Hydrogenated soy phosphatidylcholine used as an emulsifier that effectively helps to stabilize and blend together two or more immiscible substances, making it a popular ingredient in a wide range of industries.
Among liposome excipients, there are many kinds of phospholipids. As a member of phospholipids, hydrogenated phosphatidylcholine can participate in the formation of liposomes and the use of hydrogenated soy phosphatidylcholine cas 92128 87 5 has important application prospects in drug delivery.
Synthetic phospholipids, including hydrogenated phosphatidylcholine, are preferred excipients with characteristics of stable properties, anti-oxidation, and stabilizing the finished products.
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