In the field of medicine, fat emulsion injections like clevidipine lipid emulsion are frequently used as a submicroemulsion injection with lipid microspheres serving as the drug carrier. Meanwhile, egg yolks are a known source of lecithin, a phospholipid that is often utilized in the production of lipid emulsion injections like clevidipine.
1. Intralipid emulsion of fat excipent egg yolk lecithin is used as emulsifier in nutritional and therapeutic injectable lipid emulsions (intralipid emulsion therapy), presenting excellent emulsifying properties and ability to enhance the emulsion stablity.
2. The egg yolk lecithin is soluble in soybean oil at 60°C, which is easy to process in preparation.
3. The egg yolk lecithin keeps the emulsion in a relatively stable particle size and pH, and prolongs the validity period of the emulsion.
4. Oleic acid can be used as co-emulsifier in lipid emulsions to improve the emulsification of lipids effect and enhance the stability of the emulsion.
Fat emulsion injection excipents egg yolk lecithin is the only emulsifier with better safety profile and it can be used for emulsion parenteral. Its emulsification efficacy is a critical determining factor to the quality of lipid emulsions.
Fat emulsion uses oleic acid as co-emulsifier in lipid emulsions to improve the emulsification effect and enhance the stability of the emulsion.
Utilize excipients approved for parenteral use.
Select as less types and volumes of excipients as possible in injections,
like intralipid 20% 100ml or intralipid 10% 500ml, while meeting the requirement.
Utilize excipients which are commonly used in injections as much as possible,
for example, the clevidipine lipid emulsion excipient.
If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.