Trometamol hydrochloride (Tris-HCl) is used in many applications within molecular biology laboratories as a buffering agent. It is also extensively employed in the preparation of antibody drugs, nucleic acid drugs, and vaccines.
NMPA CDE registration no.: F20220000346
USFDA DMF no.: 038022
| Product Name | Trometamol hydrochloride；TRIS-HCL |
| Chemical Name | Tris(hydroxymethyl)aminomethane hydrochloride |
| CAS No. | 1185-53-1 |
| NMPA CDE registration no. | F20220000346 |
| USFDA DMF No. | 038022 |
| Quality grade | Injection |
| Quality standards | Comply with ChP, USP, EP or other pharmacopoeia standards |
| Molecular Formula | C4H12CINO3 |
| Applications and examples | Monoclonal and bispecific antibodies, Antibody-drug conjugates (ADC), liposomes, nucleic acid drugs, vaccines and other premium preparation |
| Product code | A03002 |
| Package sizes | 1kg |
| Storage condition | It should be stored in well-closed containers, protected from light. It should be retested every 2 years when used and stored properly. |
Tris-HCl offers the following advantages: high solubility in water resulting in clear solutions; high purity up to 99.6%, with stable performance; no precipitation with certain metal ions (such as calcium and magnesium); low ionic strength; superior performance over traditional phosphate buffer systems in enzyme assays.
Tris-HCl effectively stabilizes the pH of a solution and maintains the physical stability of macromolecular drugs to prevent their degradation or aggregation during the experiment.
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