AVT (Shanghai) Pharmaceutical Tech Co., Ltd.

1,2-Dierucoyl-sn-glycero-3-phosphocholine(for injection) DOPC

The injection-grade DOPC supplied by A.V.T. features high stability and purity, making it suitable for use as a membrane material in liposomes. Due to its lower phase transition temperature and susceptibility to oxidation owing to its double bond structure, its application is not as widespread as that of DSPC, HSPC, and others. However, it serves as a crucial excipient in many commercially available liposomal products, such as liposomal cytarabine, liposomal morphine sulfate, Epaxal, Inflexal V, and Shingrix. 

NMPA CDE registration no.: F20190000371

USFDA DMF no.: 028883


Product Name1,2-Dierucoyl-sn-glycero-3-phosphocholine(for injection) DOPC
Chemical Name/


NMPA CDE registration no.F20190000371
USFDA DMF No.28883
Quality gradeinjection
Quality standardsConforms with USP、JP、ChP standards
Molecular FormulaC44H84NO8P
Applications and examplesCytarabine, Morphine Sulfate Liposomes
Product codeS01007
Package sizes1kg
Storage condition


Its lower phase transition temperature makes it suitable for liposome preparation;

Its unsaturated fatty acid tail structure renders the liposome membrane more prone to disruption, aiding in the release of payloads and thereby enhancing mRNA delivery effectiveness.


DOPC (18:1 PC) tends to be viscous, prone to lump formation, and susceptible to moisture absorption. Therefore, special attention should be paid for storage, preferably at -20°C, with proper sealing and protection from light to prevent any adverse effects on its quality and shelf life. Additionally, as phospholipids are prone to hydrolysis in strong acidic or alkaline environments, it is important to avoid DOPC contact with strong acid or alkali media.

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