Phosphatidic Acid is produced by phospholipase D through the hydrolysis of phosphatidylcholine. The compound has been reported to activate the mitogen-activated protein kinase (MAPK) cascade, and interacts with Raf-1 by binding and mediating its translocation to the plasma membrane. Studies show that Phosphatidic Acid is an intracellular pH biosensor and couples metabolism to membrane biogenesis.
| Chemical name | 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium |
| Molecular formula | C35H68O8PNa |
| CAS number | 169051-60-9 |
| Manufacturer | AVT (Shanghai) Pharmaceutical Tech Co., Ltd. / A.V.T. |
| Grade | reagent grade |
| NMPA registration number | N/A |
| DMF number | N/A |
| EINECS number | N/A |
| Specifications | in-house |
| Description | white powder |
| Purity | N/A |
| Solubility | N/A |
| Molecular weight | 692.85 |
| pKa | N/A |
| Phase transition temperature | unknown |
16:0 DPPA can serve as a lipid standard for quantitatively detection of lipids that are expressed within an animal cell and released by E-SYT2.
DPPA serves as a regulator of respiratory burst in phagocytes and is a precursor to diacylglycerol and lyso-phosphatidic acid. 16:0 DPPA can enhance the bactericidal effect of eugenol.
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