AVT (Shanghai) Pharmaceutical Tech Co., Ltd.
alc 0159


ALC-0159 is a PEGylated lipid excipient. It can combine with ALC-0315, cholesterol and DSPC to form lipid nanoparticles for delivery and entrapment of mRNA vaccines. Currently, ALC-0159, as a helper lipid approved for RNA therapies clinically, has been applied in the research on the mRNA (COVID-19) vaccine. Besides, it is also one of the vector components in the BNT162b vaccine against COVID-19. 


Product nameALC-0159
Chemical name2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide
CAS No.1849616-42-7
Quality standardsmanufacturer's standard
Molecular formulaC31H63NO2(C2H4O)n, n≈45
Content determination≧97%
Molecular weight2464.2
Product CodeO02009
Available Package Sizes1g




ALC-0159 is a polyethylene glycol (PEG)-lipid conjugate which can prevent elimination in vivo, thus extending the circulation time of the LNP delivery system.

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