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DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines, and in particular forms part of the drug delivery system for the Moderna COVID-19 vaccine. DMG-PEG2000 is also used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG2000 can help reduce antibody association (opsonization) by serum proteins and clearance by phagocytes thus conferring longer systemic circulation.
DMG-PEG (2000), with a CAS number of 160743-62-4, is soluble in organic solvents such as ethanol and dimethyl formamide. The solubility of DMG-PEG (2000) in these solvents is approximately 1 mg/ml. DMG-PEG(2000) is also slightly soluble in DMSO.
| Product name | DMG-PEG2000 |
| Chemical name | 1,2-dimyristoyl-rac-glycero-3-methoxypolyethylene glycol-2000 |
| CAS No. | 160743-62-4 |
| CDE Record registration Number | F20210000451 |
| FDA DMF Number | 036553 |
| Grade | Injection |
| Quality standards | manufacturer's standard |
| Molecular formula | C32H62O5(C2H4O)n, n≈45 |
| Content determination | >95% |
| DMG PEG 2000 Molecular weight | 2509.2 |
| Product Code | O02005 |
| Available Package Sizes | 1g |
DMG-PEG2000 and its derivatives such as PEG2000 C DMG and PEG DMG offer several key benefits for various biomedical and research applications.
PEG2000 DMG pharma has high purity;
PEG2000 DMG is currently undergoing CDE/DMF registration;
The Moderna COVID-19 vaccine formulation includes PEG2000 DMG among its key components.
DMG-PEG2000 boasts a high purity level.
PEG2000 DMG 1 is currently undergoing CDE/DMF registration process, further ensuring its reliability and safety for use in various pharmaceutical and research applications.
DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride.
DMG PEG 2000 is used to manufacture lnp lipid nanoparticle that are used in mRNA vaccines, and in particular forms part of the drug delivery system for the Moderna COVID-19 vaccine.
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