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Lipid nanoparticles(LNPs)

Lipid nanoparticles(LNPs)

Lipid nanoparticles (LNPs) have emerged across the pharmaceutical industry as promising vehicles to deliver a variety of therapeutics. LNPs hold great promise in genetic medicine where gene editing, vaccine development, immuno-oncology, and other genetic therapies rely on the ability to efficiently deliver nucleic acids into cells. LNPs have advantages over other gene and vaccine delivery systems because they are easier to manufacture, are less immunogenic, can carry larger payloads, and can be designed for multiple dosages. The successful use of LNPs as a delivery vector for the COVID-19 mRNA vaccines will likely broaden the horizons for research in mRNA vaccines.

  • Dlin-MC3-DMA


    DLin-MC3-DMA is one of the most utilized ionizable amino lipids (apparent pKa = 6.44) that is used for making lipid nanoparticles (LNPs) which can encapsulate and deliver siRNA, mRNA, DNA, or small mo...
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  • SM 102 LIPID

    SM 102 LIPID

    SM102(Formal Name:8-[(2-hydroxyethyl)[6-oxo-6-(undecyloxy)hexyl]amino]-octanoic acid, 1-octylnonyl ester,CAS Number:2089251-47-6)is an ionizable amino lipid that can be used for the formation of lipid nanoparticles (LNPs...
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  • ALC-0315


    ALC-0315 is an ionizable aminolipid with pH variability and is biodegradable due to the introduction of an ester bond in the lipid tail.It is suitable for the prescription of lipid delivery systems fo...
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  • DSPC


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  • DOPC


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  • DMG-PEG2000


    DMG-PEG 2000 is a synthetic lipid formed by the PEGylation of myristoyl diglyceride. It is used to manufacture lipid nanoparticles that are used in mRNA vaccines, and in particular forms part forms pa...
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  • DSG-PEG2000


    DSG-PEG2000(PEG-1,2-distearoyl-rac-glycero-3-methylpolyoxyethylene 2000)is a lipid and peg conjugate which used for lipid nanoparticles preparation. Similar to DMG-PEG2000, DSG-PEG2000 has become known for li...
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  • ALC-0159


    ALC-0159 cas: 1849616-42-7 is a polyethylene glycol (PEG)-lipid conjugate also called a PEGylated lipid which has been used to form lipid nanoparticles (LNPs) for delivery of RNA. According to public ...
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  • CHOL (plant)

    CHOL (plant)

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  • DOPE


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