AVT (Shanghai) Pharmaceutical Tech Co., Ltd.
tromethamine for injection tris

Tromethamine (for injection) TRIS

AVT has newly launched tromethamine (TRIS) CAS NO 77 86 1. Tromethamine Tris base is a buffer salt widely used in the field of biomedicine and tromethamine tris buffer is in the process of NMPA and US FDA registration. The tris tromethamine advantages including high purity, low impurities, production in accordance with GMP guideline, that is tromethamine gmp/tris gmp, stable supply and high cost-effective. As a pharma excipients supplier who is committed to pharmaceutical excipients wholesale, AVT can provide high-level pharma excipients for injections ,including tris usp wholesale.

Specifications of Tromethamine (for injection) TRIS

Product nameTris (hydroxymethyl) aminomethane
CAS No.77-86-1
CDE Record registration NumberNo.:F20220000153
FDA DMF Number37604
Quality standardsComply with ChP, USP, EP or other pharmacopoeia standards

Sufficient supply, cost-effective
DescriptionManufactured in GMP facility, injection-grade, ultra-low endotoxin (< 4 IU/g)
ApplicationsMonoclonal and bispecific antibodies, Antibody-drug conjugates (ADC), liposomes, nucleic acid drugs, vaccines and other premium preparation
Product CodeA02012

Tromethamine (Tris) is an organic compound widely used in the preparation of buffers for biochemistry and molecular biology experiments, serving as a key component in protein electrophoresis buffers. Tris also plays a very important role in such pharmaceutical formulations as mRNA vaccines, antibody-drug conjugates (ADCs), and contrast agents.


We supply Tris meeting the quality standards specified in the Chinese Pharmacopoeia (ChP), United States Pharmacopeia (USP), Japanese Pharmacopoeia (JP), and European Pharmacopoeia (EP), enabling NMPA/FDA registration submission. Manufactured in GMP-compliant facilities, it boasts low endotoxin levels and is readily available in stock. Due to ample production capacity and cost-effectiveness, our Tris product is highly competitive in the market.


Tris is primarily used as a buffering system in pharmaceutical formulations such as mRNA vaccines, antibody-drug conjugates (ADCs), contrast agents, etc., stabilizing nucleic acid macromolecules and enhancing cellular transfection efficiency.

Key Benefits of Tromethamine Tris

  • Tromethamine (Tris) is a buffer salt widely used in the field of biomedicine. It is white crystalline particles, commonly used in protein or nucleic acid buffers. The effective range is usually between pH 7.0-9.2.

  • Tris is used for the growth of protein crystals under different pH conditions. Tris is also one of the main components of protein electrophoresis buffer. It forms a buffer system with glycine in the electrophoresis buffer to stabilize the pH during electrophoresis.

  • In addition, Tris is also an intermediate in the preparation of surfactants, vulcanization accelerators and some drugs. Titration standard substance is also its usage.

Have Any Questions?

If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.

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