liposomal Phospholipids (used to prepare liposomes) are divided to natural phospholipids and synthetic phospholipids.
AVT, the phosphatidylcholine liposomal manufacturer, is specialized in drug delivery systems such as liposomes, lipid emulsions, and micro-nano targeted formulations.
Our products cover natural phospholipids, synthetic phospholipids, functionalized phospholipids, nucleic acid delivery and other sub-fields.
liposomal Phospholipids are used as skeleton membranes of liposomes.
liposomal Phospholipids used to prepare liposomes include natural phospholipids and synthetic phospholipids.
Synthetic phospholipids are preferred excipients with characteristics of stable properties, anti-oxidation, and stabilizing the finished products.
1. Liposomes are composed of phospholipids as the skeleton membrane and additives. The phospholipids used to prepare liposomes include natural phospholipids and synthetic phospholipids.
2. Additives, such as cholesterol, are needed to prepare liposomes. liposome phospholipid undergoes a mixture with Cholesterol, which is also an amphiphilic substancear, to prepare stable liposomes. Its function is to adjust the fluidity of the bilayer and reduce the liposomes membrane permeability.
3. In the liposome formulation, special excipients are also utilized. For example, irinotecan liposome Onivyde® uses sucrose octasulfate for gradient drug loading.
4. The lyophilized liposome generally uses sucrose or trehalose as the cryoprotectant for lyophilization.
If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.