AVT (Shanghai) Pharmaceutical Tech Co., Ltd.
Phospholipids(for liposomes)

Phospholipids(for liposomes)

liposomal Phospholipids (used to prepare liposomes) are divided to natural phospholipids and synthetic phospholipids.

As a leading phosphatidylcholine liposomal manufacturer, AVT specializes in developing drug delivery systems that utilize liposomes, lipid emulsions, and micro-nano targeted formulations. In particular, our liposome phospholipid undergoes a meticulous manufacturing process, ensuring the highest standards of quality and efficacy of their drug delivery systems.

Our products cover natural phospholipids, synthetic phospholipids, functionalized phospholipids, nucleic acid delivery and other sub-fields.


TYPES OF LIPOSOMAL PHOSPHOLIPIDS (FOR LIPOSOMES)

HSPC/Hydrogenated Soy Phosphatidylcholine Cas 92128 87 5

HSPC/Hydrogenated Soy Phosphatidylcholine Cas 92128 87 5

liposomal Phospholipids are used as skeleton membranes of liposomes.
Learn More
DOTAP

DOTAP

DOTAP is an effective cationic lipid, originally utilized in commercial products as a gene transfection reagent. It is also applicable as a pharmaceutical excipient in liposomal formulations. Its notable application is EndoTAG-1, a cationic liposomal formulation of paclitaxel. DOTAP imparts a positive charge to EndoTAG-1, allowing it to selectively adhere to tumor endothelial cells (TECs) with negative charges. This selective adsorption facilitates targeted attack on tumor neovasculature without harming healthy vessels, effectively inhibiting tumor growth.
Learn More
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)

DPPC is a synthetic phospholipid with a purity of at least 98.0% and can be used as a lipid membrane material in the preparation of liposomes.DPPC is also an endogenous substance and is the main compo...
Learn More
Dimyristoyl Phosphatidylcholine

Dimyristoyl Phosphatidylcholine

Dimyristoylphosphatidylcholine(DMPC) is a phosphatidylcholine, a kind of phospholipid. As a phospholipid, DMPC can form a micelle with a hydrophobic core to contain lipophilic drugs while maintaining a hydrop...
Learn More

Liposomal Phospholipids (For Liposomes) Effects

01

liposomal Phospholipids are used as skeleton membranes of liposomes.

02

liposomal Phospholipids used to prepare liposomes include natural phospholipids and synthetic phospholipids.

03

Synthetic phospholipids are preferred excipients with characteristics of stable properties, anti-oxidation, and stabilizing the finished products.

How do Phospholipids (For Liposomes) Work?

How do Phospholipids (For Liposomes) Work?

1. Liposomes are composed of phospholipids as the skeleton membrane and additives. The phospholipids used to prepare liposomes include natural phospholipids and synthetic phospholipids.

2. Additives, such as cholesterol, are needed to prepare liposomes. liposome phospholipid undergoes a mixture with  Cholesterol, which is  also an amphiphilic substancear, to prepare stable liposomes. Its function is to adjust the fluidity of the bilayer and reduce the liposomes membrane permeability.

3. In the liposome formulation, special excipients are also utilized. For example, irinotecan liposome Onivyde® uses sucrose octasulfate for gradient drug loading.

4. The lyophilized liposome generally uses sucrose or trehalose as the cryoprotectant for lyophilization.

Have Any Questions?

If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.

Contact us
sales@avt-cn.com
Address
Room A, 27th Floor, Huadu Mansion, No.838, Zhangyang Road, Pudong District, Shanghai.
Contact AVT
Your Name *
Your Email *
Your Phone
Type Service
Your Message *