AVT (Shanghai) Pharmaceutical Tech Co., Ltd.


ALC0315 C48H95NO5 CAS No.2036272-55-4

ALC-0315 is an ionizable aminolipid with pH variability and is biodegradable due to the introduction of an ester bond in the lipid tail.

ALC-0315 is suitable for the prescription of lipid delivery systems for various nucleic acid drugs and nucleic acid vaccines. ALC 0315 use also be found in compressing mRNA, thereby contributing significantly to cellular delivery and cytoplasmic release of mRNA.

ALC0315 is responsible for the cellular delivery and cytoplasmic release of mRNA and is used as a component of lipid nanoparticle (LNP) delivery vehicles for the delivery of mRNA-based vaccines. 

ALC o315 has numerous advantages in various biomedical applications, which include the ability to tune lipid interactions, modulate charge and endosomal release, and facilitate endosomal escape.

 ALC-0315 C48H95NO5 Specifications

Product nameALC-0315
Chemical name[(4-Hydroxybutyl)azanediyl]di(hexane-6,1-diyl) bis(2-hexyldecanoate)
CAS No.2036272-55-4
EINECS registration Number/
CDE Record registration Number/
FDA DMF Number/
Quality standardsmanufacturer's standard
Molecular formulaC48H95NO5
Content determination≧98%
Molecular weight766.3
Product CodeO02008
Available Package Sizes1g

ALC-0315 C48H95NO5 Key Benefits 

The compound C48H95NO5, also known as ALC_0315, is a pH-sensitive cationic lipid which is used in the Pfizer/BioNTech Covide-19 vaccine Comirnaty to improve the vaccine's effectiveness.

ALC-0315 C48H95NO5 Advantages and Applications 

ALC 0315 uses widely in various biomedical applications

ALC0315 is a pH-sensitive cationic lipid from professional ALC 0315 manufacturer AVT ltd

ALC-0315 is a synthetic lipid. 

ALC 0315 is a colorless oily material. 

ALC-0315 is one of the components of the BNT162b2 vaccine (Comirnaty).

Overall, the use of ALC 0315 in biomedical applications shows great promise, and further research is required to explore more of its potential advantages and applications.

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