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phospholipids for liposomes


DPPC cas no:. 63-89-8 is a synthetic phospholipid with a purity of at least 98.0% and can be used as a lipid membrane material in the preparation of liposomes.

DPPC is also an endogenous substance and is the main component of the human lung surface active substance, accounting for more than 60%. It is distributed on the surface of the alveolar

It has the effect of reducing the surface tension of the alveoli, maintaining the relative stability of the alveolar volume and preventing the transfer of fluid from the alveolar capillaries to the alveoli.

It is also used as an exogenous source of fluid in the alveoli. DPPC is also used as an exogenous pulmonary surfactant, for example in Survanta and Beraksurf.

It is also a major component of the prescription of liposomal lung inhalers, such as Arikayce liposomal .

Specifications of 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC) CAS: 63-89-8

Product name1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)
Chemical name(R)-2,3-bis(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
CAS No.63-89-8
CDE Record registration Number/
FDA DMF Number/
Quality standards/
Molecular formulaC40H80NO8P
Content determination99.86%
Molecular weight734.06
Available Package Sizes/

Advantages and Applications of 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine(DPPC)

CDE/DMF registration; in stock; High purity

It is the main constituent of pulmonary surfactants, which reduces the work of breathing and prevents alveolar collapse during breathing. It also plays an important role in the study of cationic liposomes and human bilayers. Dipalmitoylphosphatidylcholine (DPPC) is also used to formulate some medicines used for treatment of respiratory distress syndrome (RDS) in newborns.

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