AVT (Shanghai) Pharmaceutical Tech Co., Ltd.
cho hp


The high-purity cholesterol (CHO-HP) supplied by V.A.T. is suitable for the preparation of fat emulsions and liposomes. Compared to its role as an emulsifier in fat emulsions, CHO is more widely used in liposome preparation. It has been extensively employed as a membrane material in commercially available liposomal products and liposomal products (such as Lipoplatin, a liposomal cisplatin) at clinical stages.

Product Description

Product nameHigh purity cholesterol CHO-HP
Chemical nameCholesterol, 5-Cholesten-3β-ol
Molecular formulaC27H46O
CAS No.57-88-5
CDE Record registration NumberF20170000106(A)
FDA DMF Number
Quality standardsConforms with USP, EP, JP, ChP standards

Sufficient supply, cost-effective
Descriptionwhite powder
ApplicationsLiposomes, regulate phospholipid membrane fluidity
Product CodeO01001
Available Package Sizes

Key Benefits of CHO-HP

CHO can insert into the phospholipid bilayer of liposomes, interacting with phospholipid molecules to modulate the fluidity of the liposome membrane. Its effect varies with temperature changes;

As CHO is amphiphilic, possessing both hydrophilic and hydrophobic properties, it can enhance the stability of liposomes by regulating the liposome membrane.

CHO-HP Product Properties

Cholesterol, also known as cholestane, is a cyclopentane polyhydrophenanthrene derivative. At temperatures above the phase transition temperature, CHO reduces the mobility of phospholipid fatty acid chains, thereby decreasing the fluidity of phospholipid molecules. Conversely, at temperatures below the phase transition temperature, it prevents the interaction between phospholipid fatty acid chains, thereby preventing a significant decrease in the fluidity.

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If you have any questions, please don't hesitate to contact us. We're always here to help with Pharmaceutical Excipients for your business. We can provide products ranging from grams to tons. AVT is able to produce and even register the product in US FDA according to your special needs.

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